Pskov region is located in the north-west of Russia. It borders on Latvia and Estonia to the west, the Republic of Belarus and the Smolensk Region to the south, the Leningrad Region to the north and northeast, the Novgorod Region to the east, and the Tver Region to the southeast.

The highways Moscow — Riga; St. Petersburg-Kiev — Odessa; St. Petersburg — Vilnius; St. Petersburg-Riga, etc. pass through the region.
Railway routes: Moscow-Riga; Saint Petersburg-Odessa; Saint Petersburg-Vilnius — Kaliningrad; Saint Petersburg-Riga; Saint Petersburg — Lviv, etc.
The main river is the Great One. On the territory of the region there are Pskov and Peipus Lakes (most of them are located outside the territory of the region).

The leading place in the industry is occupied by mechanical engineering, including the electrical industry, the production of equipment for the chemical and textile industries, peat-mining machines, and the radio-electronic industry. In addition, the region has developed light, food, and woodworking industries, as well as the production of building materials.

In agriculture, dairy farming prevails, in crop production — the cultivation of forage crops.